On most computers, you can resume working by pressing your computer’s power button. However, not all computers are the same. You might be able to wake your computer by pressing any key on the keyboard, clicking a mouse button, or opening the lid on a laptop.
For a desktop PC pressing any key on the keyboard and clicking a mouse button are the most common ways to wake up system, but some user don’t want to wake up their system by an accidental key press or a mouse click.
To help those who don’t want to wake up their system by these accidental key press and clicks here is an workaround which can help you to disable Key press and Mouse click system’s wake up capability (not recommended). To do this follow the below steps-
Step 1. Press WIN + PauseBreak to open System Properties or right click on My Computer and chose Properties.
Step 2. Now click on Device Manager to launch it.

Step 3. Now choose Keyboards > Standars PS/2 Keyboard and right click on it and select Properties

Step 4. Now go to Power Management tab and un-check the option “Allow this device to wake up the computer“.

That’s it, you can do the same for Mouse by un-checking the option in “Mice and other Pointing device”
Is there any way that we can shut down/sleep/hibernate our desktop PCs using keyword or mouse by a single click?
umm……You can add desktop shortcuts for them.
Create Shortcuts by using this simple program created by me http://beingpc.com/2009/12/create-shortcuts-easily-by-using-handy-shortcuts/
This is a very useful article for me and my computer of course!